PERBEDAAN KADAR SERUM GLUTAMIC PYRUVIC TRANSAMINASE (SGPT) PADA REMAJA PEMINUM DAN BUKAN PEMINUM ARAK BALI DI DESA TAMANBALI KABUPATEN BANGLI

Paramita, I Dewa Ayu Intan Adelia (2025) PERBEDAAN KADAR SERUM GLUTAMIC PYRUVIC TRANSAMINASE (SGPT) PADA REMAJA PEMINUM DAN BUKAN PEMINUM ARAK BALI DI DESA TAMANBALI KABUPATEN BANGLI. Diploma thesis, Poltekkes Kemenkes Denpasar Jurusan Teknologi Laboratorium Medis 2025.

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Abstract

DIFFERENCE IN SERUM GLUTAMIC PYRUVIC TRANSAMINASE (SGPT) Levels BETWEEN ADOLESCENT DRINKERS AND NON-DRINKERS OF BALI ARAK IN TAMANBALI VILLAGE, BANGLI REGENCY ABSTRAK Background: the liver is a vital organ that plays a key role in the metabolism of harmful substances such as alcohol. Alcohol consumption, particularly arak bali, can lead to impaired liver function, which is characterized by an increase in Serum Glutamic Pyruvic Transaminase (SGPT) levels. In Tamanbali Village, Bangli Regency, there is a noticeable tendency of high arak bali consumption, especially among adolescents. Objective: this study aims to determine the SGPT levels in adolescents who consume and do not consume arak bali, as well as to identify the differences in SGPT levels between these two groups in Tamanbali Village, Bangli Regency. Method: this is a quantitative study with a cross-sectional design. The samples were taken from adolescents in Tamanbali Village, and SGPT levels were measured using the enzymatic kinetic method with a semi-automatic spectrophotometer. Data analysis included the Shapiro-Wilk test for normality and the Independent Sample T-Test for hypothesis testing. Results: there was a significant difference in SGPT levels between adolescents who konsumed arak bali and those who did not. The Independent Sample T-Test showed a significance value of 0.012 (< 0.05), indicating a statistically significant difference. The group of alcohol consumers had higher SGPT levels compared to the non-consumer group. Conclusion: the habit of consuming arak bali among adolescents can increase SGPT levels, indicating a risk of liver dysfunction. Therefore, education and awareness programs are necessary to inform the community, especially adolescents, about the health risks of alcohol consumption on liver function. Keywords: Arak bali, adolescents, SGPT PERBEDAAN KADAR SERUM GLUTAMIC PYRUVIC TRANSAMINASE (SGPT) PADA REMAJA PEMINUM DAN BUKAN PEMINUM ARAK BALI DI DESA TAMANBALI KABUPATEN BANGLI ABSTRAK Latar Belakang: hati merupakan organ penting yang berperan dalam metabolisme zat berbahaya seperti alkohol. Konsumsi alkohol, khususnya arak bali, dapat menyebabkan gangguan fungsi hati yang ditandai dengan peningkatan kadar Serum Glutamic Pyruvic Transaminase (SGPT). Di Desa Tamanbali, Bangli, terdapat kecenderungan konsumsi arak bali yang cukup tinggi, terutama di kalangan remaja. Tujuan: penelitian ini bertujuan untuk mengetahui kadar SGPT pada peminum dan bukan peminum arak bali serta mengetahui perbedaan kadar SGPT antara remaja peminum dan bukan peminum arak bali di Desa Tamanbali, Kabupaten Bangli. Metode: jenis penelitian ini adalah kuantitatif dengan desain cross-sectional. Sampel diambil dari remaja di Desa Tamanbali, kemudian dilakukan pengukuran kadar SGPT menggunakan metode kinetik enzimatik dengan alat spektrofotometri semi-otomatis. Data dianalisis menggunakan uji Shapiro-wilk pada uji normalitas dan pada uji hipotesis menggunakan uji Independent Sample T-Test . Hasil: tedapat perbedaan kadar SGPT antara remaja peminum dan bukan peminum arak bali, yang dibuktikan dengan uji Independent Sample T-Test yang dimana di dapatkan hasil sig 0,012 (<0,005), hal tersebut menunjukan bahwa terdapat perbedaaan anatara kadar SGPT kelopok peminum arak bali dan bukan peminum arak bali,. di mana kelompok peminum menunjukkan kadar SGPT yang lebih tinggi dibandingkan kelompok bukan peminum. Kesimpulan: kebiasaan konsumsi arak bali pada remaja dapat peningkatkan kadar SGPT, yang menunjukkan adanya risiko gangguan fungsi hati. Diperlukan edukasi kepada masyarakat, khususnya remaja, mengenai bahaya konsumsi alkohol terhadap kesehatan hati. Kata kunci: arak bali, remaja, SGPT

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