ANALISIS KADAR SERUM GLUMATIC PYRUVIC TRANSAMINASE PADA REMAJA PEROKOK ELEKTRIK DAN KONVENSIONAL DI DESA PEJENG KANGIN KECAMATAN TAMPAKSIRING KABUPATEN GIANYAR

Safitri, Ni Wayan Elina Diah (2025) ANALISIS KADAR SERUM GLUMATIC PYRUVIC TRANSAMINASE PADA REMAJA PEROKOK ELEKTRIK DAN KONVENSIONAL DI DESA PEJENG KANGIN KECAMATAN TAMPAKSIRING KABUPATEN GIANYAR. Diploma thesis, Poltekkes Kemenkes Denpasar Jurusan Teknologi Laboratorium Medis 2025.

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Abstract

ANALYSIS OF SERUM GLUMATIC PYRUVIC TRANSAMINASE LEVELS IN TEENAGERS WHO ARE ELECTRIC AND CONVENTIONAL SMOKERS IN PEJENG KANGIN VILLAGE, TAMPAKSIRING DISTRICT, GIANYAR REGENCY ABSTRACT Smoking habits both conventional and electronic are increasingly common among teenagers. Conventional cigarettes contain tar, nicotine, and around 4000 dangerous chemical compounds, such as carbon monoxide and formaldehyde, while electronic cigarettes use a device that converts nicotine and other chemicals into vapor that can affect liver function, one of which is indicated by increased levels of Serum Glutamic Pyruvic Transaminase (SGPT). This study aims to compare SGPT levels in adolescent users of electronic cigarettes and conventional cigarettes. The research design used was descriptive analytical with a cross-sectional approach. The study was conducted from February to April in Pejeng Kangin Village. The study population was adolescent smokers with a sample size of 42 consisting of 21 electric smokers and 21 conventional smokers. The sample was determined using the Lemeshow formula and selected through a purposive sampling technique. SGPT examination was carried out at Sanjiwani Hospital using the spectrophotometry method and the data were analyzed using the Independent t-test. The results showed that the average SGPT level of conventional smokers was 31.24 U/L while that of electronic smokers was 24.10 U/L. There was a difference in SGPT levels between conventional smokers and electronic smokers (significance = 0.000). SGPT levels in the conventional smoker group were higher than Serum Glutamic Pyruvic Transaminase levels in the electronic smoker group. Keywords: e-cigarettes, conventional cigarettes, Serum Glutamic Pyruvic Transaminase ANALISIS KADAR SERUM GLUMATIC PYRUVIC TRANSAMINASE PADA REMAJA PEROKOK ELEKTRIK DAN KONVENSIONAL DI DESA PEJENG KANGIN KECAMATAN TAMPAKSIRING KABUPATEN GIANYAR ABSTRAK Kebiasaan merokok baik konvensional maupun elektrik semakin marak di kalangan remaja. Rokok konvensional mengandung tar, nikotin, dan sekitar 4000 senyawa kimia berbahaya, seperti karbon monoksida dan formaldehida sedangkan rokok elektrik menggunakan perangkat yang mengubah cairan nikotin dan bahan kimia lainnya menjadi uap yang dapat berdampak pada fungsi hati salah satunya ditandai dengan peningkatan kadar Serum Glutamic Pyruvic Transaminase (SGPT). Penelitian ini bertujuan untuk membandingkan kadar SGPT pada remaja pengguna rokok elektrik dan konvensional. Desain penelitian yang digunakan adalah deskriptif analitik dengan pendekatan cross-sectional. Penelitian dilaksanakan pada bulan Februari sampai April di Desa Pejeng Kangin. Populasi penelitian adalah remaja perokok dengan jumlah sampel 42 yang terdiri dari 21 perokok elektrik dan 21 perokok konvensional. Sampel ditentukan menggunakan rumus Lemeshow dan dipilih melalui teknik purposive sampling. Pemeriksaan SGPT dilakukan di RSUD Sanjiwani dengan metode spektrofotometri dan data dianalisis menggunakan uji Independent t-test. Rerata kadar SGPT perokok konvensional sebesar 31,24 U/L sedangkan perokok elektrik sebesar 24,10 U/L. Terdapat perbedaan kadar SGPT antara perokok konvensional dengan perokok elektrik (signifikansi = 0,000). Kadar SGPT pada kelompok perokok konvensional lebih tinggi dari pada kadar SGPT pada kelompok perokok elektrik. Kata Kunci: Perokok konvensional, Perokok elektrik, Serum Glutamic Pyruvic Transaminase

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