ANALISIS HUBUNGAN FAKTOR USIA, JENIS KELAMIN, RIWAYAT KLINIS HIV, DAN DM TERHADAP HASIL PEMERIKSAAN GENEXPERT PADA SUSPEK TUBERKULOSIS DI RSD MANGUSADA

Narayendra, I Kadek Putra (2026) ANALISIS HUBUNGAN FAKTOR USIA, JENIS KELAMIN, RIWAYAT KLINIS HIV, DAN DM TERHADAP HASIL PEMERIKSAAN GENEXPERT PADA SUSPEK TUBERKULOSIS DI RSD MANGUSADA. Diploma thesis, Poltekkes Kemenkes Denpasar, Teknologi Labortorium Medis 2026.

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Abstract

ANALYSIS OF THE RELATIONSHIP BETWEEN AGE, GENDER, HIV CLINICAL HISTORY, AND DIABETES MELLITUS ON GENEEXPERT TEST RESULTS IN TUBERCULOSIS SUSPECTS AT MANGUSADA HOSPITAL ABSTRACT Background: Tuberculosis (TB) remains a major public health problem in Indonesia. GeneXpert is a rapid diagnostic method capable of detecting Mycobacterium tuberculosis. Age, sex, Human Immunodeficiency Virus (HIV), and Diabetes Mellitus (DM) are suspected to be associated with GeneXpert examination results among suspected TB patients. Objective: To determine the association between age, sex, clinical history of HIV and DM, and GeneXpert examination results among suspected tuberculosis patients at Mangusada Regional Hospital. Methods: An analytic correlational study with a cross- sectional design was conducted using secondary data obtained from the Tuberculosis Information System (SITB) and Laboratory Information System (LIS). A total of 176 respondents were selected through purposive sampling. Data were analyzed using the Chi-Square test. Results: Of the respondents, 43 (24.43%) had MTB detected results, while 133 (75.57%) had MTB not detected results. Chi-Square analysis showed significant associations between age (p=0.000), sex (p=0.036), and clinical history of HIV and DM (p=0.002) with GeneXpert examination results. Conclusion: Age, sex, clinical history of HIV, and Diabetes Mellitus were significantly associated with GeneXpert examination results among suspected tuberculosis patients at Mangusada Regional Hospital. Keywords: Tuberculosis, GeneXpert, HIV, Diabetes Mellitus. ANALISIS HUBUNGAN FAKTOR USIA, JENIS KELAMIN, RIWAYAT KLINIS HIV, DAN DM TERHADAP HASIL PEMERIKSAAN GENEXPERT PADA SUSPEK TUBERKULOSIS DI RSD MANGUSADA ABSTRAK Latar Belakang: Tuberkulosis (TB) masih menjadi masalah kesehatan utama di Indonesia. Pemeriksaan GeneXpert merupakan metode diagnosis cepat yang mampu mendeteksi Mycobacterium tuberculosis. Faktor usia, jenis kelamin, HIV, dan Diabetes Melitus (DM) diduga berhubungan dengan hasil pemeriksaan GeneXpert pada suspek TB. Tujuan: Mengetahui hubungan faktor usia, jenis kelamin, riwayat klinis HIV, dan DM dengan hasil pemeriksaan GeneXpert pada suspek tuberkulosis di RSD Mangusada. Metode: Penelitian analitik korelatif dengan desain cross-sectional menggunakan data sekunder dari Sistem Informasi Tuberkulosis (SITB) dan Laboratory Information System (LIS). Sampel berjumlah 176 responden yang dipilih secara purposive sampling. Analisis data dilakukan menggunakan uji Chi-Square. Hasil: Sebanyak 43 responden (24,43%) menunjukkan hasil MTB detected dan 133 responden (75,57%) MTB not detected. Uji Chi-Square menunjukkan hubungan signifikan antara usia (p=0,000), jenis kelamin (p=0,036), serta riwayat HIV dan DM (p=0,002) dengan hasil pemeriksaan GeneXpert. Simpulan: Faktor usia, jenis kelamin, riwayat klinis HIV, dan DM berhubungan signifikan dengan hasil pemeriksaan GeneXpert pada suspek tuberkulosis di RSD Mangusada. Kata Kunci: Tuberkulosis, GeneXpert, HIV, Diabetes Melitus.

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