HUBUNGAN PEMBERIAN KEMOTERAPI DENGAN KADAR HEMOGLOBIN PADA PASIEN KANKER PAYUDARA DI RUMAH SAKIT UMUM DAERAH BALI MANDARA

Dwivayanti, Gusti Ayu Made (2026) HUBUNGAN PEMBERIAN KEMOTERAPI DENGAN KADAR HEMOGLOBIN PADA PASIEN KANKER PAYUDARA DI RUMAH SAKIT UMUM DAERAH BALI MANDARA. Diploma thesis, Poltekkes Kemenkes Denpasar Jurusan Teknologi Laboratorium Medis 2026.

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Abstract

THE RELATIONSHIP BETWEEN CHEMOTHERAPY ADMINISTRATION AND HEMOGLOBIN LEVELS IN BREAST CANCER PATIENTS AT BALI MANDARA REGIONAL GENERAL HOSPITAL ABSTRACT Background: Breast cancer is a leading cause of death among women. Chemotherapy, as a primary treatment, can cause hematological side effects, including decreased hemoglobin levels. However, evidence on the relationship between chemotherapy frequency and hemoglobin levels remains inconsistent. Objective: To determine the relationship between chemotherapy administration and hemoglobin levels in breast cancer patients at Bali Mandara Regional General Hospital. Methods: This quantitative study used a cross-sectional design. A total of 30 patients were selected through consecutive sampling. Chemotherapy frequency data were obtained from medical records, while hemoglobin levels were measured using a hematology analyzer. Data were analyzed using the Spearman Rank test. Results: Most respondents had low hemoglobin levels (80%), with values ranging from 8.9 g/dL to 14.7 g/dL. Chemotherapy frequency was equally distributed between ≤ 4 cycles and > 4 cycles (50% each). The Spearman Rank test showed a correlation coefficient (r) of -0.276 and a significance value (p) of 0.140 (p > 0.05), indicating no significant relationship. Conclusion: There is no significant relationship between chemotherapy frequency and hemoglobin levels. Other factors such as nutritional status, clinical condition, and patient characteristics may play a more important role. Keywords: chemotherapy, hemoglobin, breast cancer, anemia HUBUNGAN PEMBERIAN KEMOTERAPI DENGAN KADAR HEMOGLOBIN PADA PASIEN KANKER PAYUDARA DI RUMAH SAKIT UMUM DAERAH BALI MANDARA ABSTRAK Latar Belakang: Kanker payudara merupakan penyebab utama kematian pada wanita. Kemoterapi sebagai terapi utama dapat menimbulkan efek samping berupa gangguan hematologi, termasuk penurunan kadar hemoglobin. Namun, hubungan antara frekuensi kemoterapi dan kadar hemoglobin masih belum konsisten. Tujuan: Mengetahui hubungan pemberian kemoterapi dengan kadar hemoglobin pada pasien kanker payudara di RSUD Bali Mandara. Metode: Penelitian kuantitatif dengan desain cross-sectional. Sampel sebanyak 30 pasien dipilih dengan teknik consecutive sampling. Data frekuensi kemoterapi diperoleh dari rekam medis, sedangkan kadar hemoglobin diukur menggunakan hematology analyzer. Analisis menggunakan uji Rank Spearman. Hasil: Sebagian besar responden memiliki kadar hemoglobin rendah sebanyak 24 orang (80%), dengan nilai terendah 8,9 g/dL dan tertinggi 14,7 g/dL. Frekuensi kemoterapi terbagi sama antara ≤ 4 kali dan > 4 kali, masing-masing 15 orang (50%). Uji Rank Spearman menunjukkan koefisien korelasi (r) -0,276 dan nilai signifikansi (p) 0,140 (p > 0,05). Simpulan: Tidak terdapat hubungan signifikan antara frekuensi kemoterapi dan kadar hemoglobin. Faktor lain seperti status gizi, kondisi klinis, dan karakteristik pasien lebih berperan. Kata kunci: kemoterapi, hemoglobin, kanker payudara, anemia

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