HUBUNGAN KADAR GLUKOSA DARAH PUASA DENGAN KADAR KREATININ PADA PENDERITA DIABETES MELITUS TIPE 2 DI RSUD TABANAN

Iswari Y, Ni Putu Syanindita Kania (2025) HUBUNGAN KADAR GLUKOSA DARAH PUASA DENGAN KADAR KREATININ PADA PENDERITA DIABETES MELITUS TIPE 2 DI RSUD TABANAN. Diploma thesis, Poltekkes Kemenkes Denpasar Jurusan Teknologi Laboratorium Medis 2025.

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Abstract

THE RELATIONSHIP BETWEEN FASTING BLOOD GLUCOSE LEVELS AND CREATININE LEVELS IN TYPE 2 DIABETES MELITUS PATIENTS AT TABANAN REGIONAL HOSPITAL ABSTRACT Background: Diabetes melitus is a chronic disease caused by insufficient insulin production, causing an accumulation of sugar levels in the body (Hyperglycemia). Increased blood sugar levels will cause sufferers to be at risk of experiencing decreased kidney function. Decreased kidney function can be indicated by increased creatinine levels in the blood. The purpose of the study was to determine the relationship between fasting blood glucose levels and creatinine levels in patients with Type 2 diabetes melitus. Method: This type of research is observational analytic with a cross-sectional research design. The study was conducted at Tabanan Regional Hospital in March-April 2025. The population of this study were patients with type 2 diabetes melitus with a sample of 43 respondents calculated using the Slovin formula with a purposive sampling technique. Fasting blood glucose and creatinine examinations were carried out using the enzymatic method. Data analysis using the chi-square test. Results: Fasting blood glucose levels in the normal category were 15 respondents (34.9%) and high category were 28 respondents (65.1%). Creatinine levels in the normal category were 15 respondents (34.9%), and high category were 28 respondents (65.1%). There is a significant relationship between fasting blood glucose levels and creatinine levels in patients with type 2 diabetes mellitus with a sig value (0.000) <0.05. Conclusion: High creatinine levels were found in many respondents with high blood sugar levels. Keywords: creatinine, fasting blood glucose HUBUNGAN KADAR GLUKOSA DARAH PUASA DENGAN KADAR KREATININ PADA PENDERITA DIABETES MELITUS TIPE 2 DI RSUD TABANAN ABSTRAK Latar Belakang: Diabetes melitus adalah penyakit kronis akibat produksi insulin yang tidak cukup, sehingga menyebabkan penumpukan kadar gula dalam tubuh (Hiperglikemia). Kadar gula darah yang meningkat akan menyebabkan penderita berisiko mengalami penurunan fungsi ginjal. Penurunan fungsi ginjal dapat ditandai dengan peningkatan kadar kreatinin dalam darah. Tujuan penelitian untuk mengetahui hubungan antara kadar glukosa darah puasa dengan kadar kreatinin pada penderita diabetes melitus Tipe 2. Metode: jenis penelitian ini adalah observasional analitik dengan desain penelitian cross-sectional. Penelitian dilaksanakan di RSUD Tabanan pada bulan Maret-April 2025. Populasi penelitian ini adalah penderita diabetes melitus tipe 2 dengan jumlah sampel 43 responden yang dihitung menggunakan rumus Slovin dengan teknik purposive sampling. Pemeriksaan glukosa darah puasa dan kreatinin dilakukan dengan metode enzimatik. Analisis data menggunakan uji chi-square. Hasil: Kadar glukosa darah puasa kategori normal sebanyak 15 responden (34,9%) dan kategori tinggi sebanyak 28 responden (65,1%). Kadar kreatinin kategori normal sebanyak 15 responden (34,9%), dan kategori tinggi sebanyak 28 responden (65,1%). Terdapat hubungan yang signifikan antara kadar glukosa darah puasa dengan kadar kreatinin pada penderita diabetes melitus tipe 2 dengan nilai sig (0,000) < 0,05. Kesimpulan: Kadar kreatinin tinggi banyak ditemukan pada responden dengan kadar gula darah tinggi. Kata kunci: glukosa darah puasa, kreatinin

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