HUBUNGAN KADAR ASAM URAT DENGAN DERAJAT HIPERTENSI PADA PASIEN PROGRAM PENGELOLAAN PENYAKIT KRONIS DI UPTD PUSKESMAS RENDANG

Putra, I Putu Bandem Arista (2026) HUBUNGAN KADAR ASAM URAT DENGAN DERAJAT HIPERTENSI PADA PASIEN PROGRAM PENGELOLAAN PENYAKIT KRONIS DI UPTD PUSKESMAS RENDANG. Diploma thesis, Poltekkes Kemenkes Denpasar Jurusan Teknologi Laboratorium Medis 2026.

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Abstract

THE CORRELATION BETWEEN URIC ACID LEVELS AND DEGREE OF HYPERTENSION IN PATIENTS OF THE CHRONIC DISEASE MANAGEMENT PROGRAM AT UPTD PUSKESMAS RENDANG ABSTRACT Background increased uric acid levels can trigger endothelial dysfunction through increased oxidative stress and decreased nitric oxide production, which plays an important role in blood vessel relaxation. The purpose of this study is to analyze the correlation between uric acid levels and the degree of hypertension in patients participating in a chronic disease management program at the Rendang Community Health Center. The study was conducted from August to October 2025 with a population of 283 people and a sample of 74 people. The method used a quantitative method with a cross-sectional design. Uric acid levels were measured using the POCT method, and hypertension degree was assessed with a tensiometer. Correlation analysis was performed using the Spearman correlation test. The result showed most respondents had high uric acid levels (86.5%) and grade I hypertension (54.1%). Respondents with normal uric acid levels were mostly in the grade I hypertension (12.2%), while those with high uric acid levels were mostly in grade II hypertension (44.6%). The Spearman test showed p 0.014 with rs = 0.285. The conclusion of the analysis shows that uric acid levels are related to the degree of hypertension in patients with chronic diseases. Keywords: hypertension, uric acid HUBUNGAN KADAR ASAM URAT DENGAN DERAJAT HIPERTENSI PADA PASIEN PROGRAM PENGELOLAAN PENYAKIT KRONIS DI UPTD PUSKESMAS RENDANG ABSTRAK Latar belakang Peningkatan kadar asam urat dapat memicu disfungsi endotel melalui peningkatan stres oksidatif dan penurunan produksi nitrit oksida, yang berperan penting dalam relaksasi pembuluh darah. Tujuan penelitian ini adalah menganalisis hubungan kadar asam urat dengan derajat hipertensi pada pasien program pengelolaan penyakit kronis di UPTD Puskesmas Rendang. Penelitian dilakukan pada bulan Agustus sampai Oktober 2025 dengan jumlah populasi 283 orang dan sampel sebanyak 74 orang. Metode penelitian ini menggunakan metode kuantitatif dengan pendekatan cross-sectional. Pemeriksaan asam urat dengan metode POCT dan pemeriksaan derajat hipertensi menggunakan tensimeter. Uji korelasi menggunakan uji Spearman. Hasil responden sebagian besar memiliki kadar asam urat dengan kategori tinggi (86,5%) dan hipertensi derajat I (54,1%). Responden dengan kadar asam urat normal sebagian besar pada hipertensi derajat I (12,2%), kadar asam urat tinggi sebagian besar memiliki hipertensi derajat II (44,6%). Uji korelasi Spearman menunjukan hasil p = 0,014 dan rs: 0,285. Simpulan hasil analisis menunjukan kadar asam urat memiliki hubungan dengan derajat hipertensi pada pasien pengelolaan penyakit kronis. Kata kunci: asam urat, hipertensi.

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