GAMBARAN JUMLAH TROMBOSIT PASKA KEMOTERAPI PADA PASIEN KANKER PAYUDARA DI RSUD BALI MANDARA

Putri, Ni Made Okta Maharani (2026) GAMBARAN JUMLAH TROMBOSIT PASKA KEMOTERAPI PADA PASIEN KANKER PAYUDARA DI RSUD BALI MANDARA. Diploma thesis, Poltekkes Kemenkes Denpasar Jurusan Teknologi Laboratorium Medis 2026.

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Abstract

DESCRIPTION OF PLATELET COUNT IN POST-CHEMOTHERAPY BREAST CANCER PATIENTS AT BALI MANDARA REGIONAL GENERAL HOSPITAL ABSTRACT Background: Breast cancer is one of the most common cancers worldwide and in Indonesia. One of the most frequently used treatment modalities is chemotherapy, which may cause side effects such as myelosuppression, including changes in platelet count. Platelet count examination is important for monitoring therapeutic response and patients' clinical conditions. Objective: This study aimed to describe post-chemotherapy platelet counts in breast cancer patients at Bali Mandara Regional General Hospital. Methods: This study employed a descriptive research design. Samples were collected using a non-probability sampling technique with a total sampling method. A total of 165 respondents were included from electronic medical record data that met the inclusion criteria. Results: The results showed that the lowest platelet count was 51,000/µL and the highest was 695,000/µL. Most patients had normal platelet counts, accounting for 135 patients (81.8%), followed by low platelet counts in 24 patients (14.6%) and high platelet counts in 6 patients (3.6%). Based on patient characteristics, normal platelet counts were most frequently observed among patients aged 45–59 years (47.9%), those with invasive carcinoma of no special type (NST) (62.4%), and those with grade II tumors (44.2%). Conclusion: Most breast cancer patients after chemotherapy had platelet counts within the normal range. Keywords: breast cancer, chemotherapy, platelet count GAMBARAN JUMLAH TROMBOSIT PASKA KEMOTERAPI PADA PASIEN KANKER PAYUDARA DI RSUD BALI MANDARA ABSTRAK Latar Belakang: Kanker payudara merupakan salah satu penyakit dengan angka kejadian tinggi di dunia maupun di Indonesia. Salah satu terapi yang sering digunakan adalah kemoterapi, yang dapat menimbulkan efek samping berupa mielosupresi, termasuk perubahan jumlah trombosit. Pemeriksaan jumlah trombosit penting dilakukan untuk memantau respons terapi serta kondisi klinis pasien. Tujuan: Penelitian ini bertujuan untuk mengetahui gambaran jumlah trombosit paska kemoterapi pada pasien kanker payudara di RSUD Bali Mandara. Metode: Penelitian ini menggunakan desain deskriptif. Pengambilan sampel dilakukan menggunakan teknik non-probability sampling dengan metode total sampling, dengan jumlah sampel 165 responden dari data rekam medis elektronik yang telah memenuhi kriteria inklusi. Hasil: Hasil penelitian menunjukkan jumlah trombosit terendah sebesar 51.000/µL dan tertinggi sebesar 695.000/µL. Sebagian besar pasien memiliki jumlah trombosit normal sebanyak 135 orang (81,8%), diikuti trombosit rendah 24 orang (14,6%) dan trombosit tinggi 6 orang (3,6%). Berdasarkan karakteristik, trombosit normal paling banyak pada usia 45–59 tahun (47,9%), tipe invasive carcinoma of no special type (NST) (62,4%), dan grade II (44,2%). Simpulan: Sebagian besar pasien memiliki jumlah trombosit dalam kategori normal. Kata kunci: kanker payudara, kemoterapi, trombosit

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