HUBUNGAN KADAR LEUKOSIT DENGAN LAJU ENDAP DARAH PADA PENDERITA TUBERKULOSIS PARU DI RUMAH SAKIT UMUM BALI JIMBARAN

Kambaniri, Made Hairani (2026) HUBUNGAN KADAR LEUKOSIT DENGAN LAJU ENDAP DARAH PADA PENDERITA TUBERKULOSIS PARU DI RUMAH SAKIT UMUM BALI JIMBARAN. Diploma thesis, Poltekkes Kemenkes Denpasar Jurusan Teknologi Laboratorium Medis 2026.

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Abstract

THE RELATIONSHIP BETWEEN LEUKOCYTE LEVELS AND ERYTHROCYTE SEDIMENTATION RATE IN PULMONARY TUBERCULOSIS PATIENTS AT BALI JIMBARAN GENERAL HOSPITAL ABSTRACT Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis and remains a major public health problem in Indonesia, including in Bali Province. TB infection can trigger an inflammatory response characterized by an increase in leukocyte levels and erythrocyte sedimentation rate (ESR). This study aimed to analyze the relationship between leukocyte levels and ESR in pulmonary tuberculosis patients at Bali Jimbaran General Hospital. The study used an observational analytic design with a cross-sectional approach involving 30 respondents selected through purposive sampling. Leukocyte examination was performed using the Hematology Analyzer, and ESR was measured using the Westergren method. The results showed that most respondents had normal leukocyte levels (53.3%) and the mean leukocyte level was 12.36 ± 6.26 × 10³/µL, while the abnormal ESR values (83.3%) and the mean ESR was 59.40 ± 40.96 mm/hour. The Spearman Rank test revealed a significant relationship between leukocyte levels and ESR (p = 0.022; r = 0.417), indicating that higher leukocyte levels were associated with higher ESR values in pulmonary tuberculosis patients at Bali Jimbaran General Hospital. Keywords: Erythrocyte Sedimentation Rate, Leukocytes, Pulmonary Tuberculosis HUBUNGAN KADAR LEUKOSIT DENGAN LAJU ENDAP DARAH PADA PENDERITA TUBERKULOSIS PARU DI RUMAH SAKIT UMUM BALI JIMBARAN ABSTRAK Tuberkulosis (TB) merupakan penyakit menular akibat Mycobacterium tuberculosis yang masih menjadi masalah kesehatan utama di Indonesia, termasuk di Provinsi Bali. Infeksi TB dapat menimbulkan respon inflamasi yang ditandai oleh peningkatan kadar leukosit dan laju endap darah (LED). Penelitian ini bertujuan menganalisis hubungan antara kadar leukosit dan LED pada penderita tuberkulosis paru di RSU Bali Jimbaran. Penelitian menggunakan desain analitik observasional dengan pendekatan cross sectional pada 30 responden yang dipilih secara purposive sampling. Pemeriksaan leukosit dilakukan dengan alat Hematology Analizer dan LED dengan metode Westergren. Hasil menunjukkan sebagian besar responden memiliki kadar leukosit normal (53,3%) dengan nilai rata-rata kadar leukosit adalah 12,36 ± 6,26 × 10³/µL dan dan LED abnormal (83,3%) dengan rata-rata LED 59,40 ± 40,96 mm/jam. Uji Spearman Rank menunjukkan hubungan signifikan antara kadar leukosit dan LED (p = 0,022; r = 0,417), yang berarti semakin tinggi kadar leukosit maka semakin tinggi pula nilai LED pada penderita tuberkulosis paru di RSU Bali Jimbaran. Kata Kunci: Laju Endap Darah, Leukosit, Tuberkulosis Paru

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