Karlina, Ni Komang Yunda (2026) ANALISIS PERBEDAAN KADAR HEMOGLOBIN SEBELUM DAN SESUDAH HEMODIALISIS PADA PASIEN GAGAL GINJAL KRONIK DI RUMAH SAKIT UMUM TABANAN. Diploma thesis, Poltekkes Kemenkes Denpasar Jurusan Teknologi Laboratorium Medis 2026.
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Abstract
ANALYSIS OF DIFFERENCES IN HEMOGLOBIN LEVELS BEFORE AND AFTER HEMODIALYSIS IN PATIENTS WITH CHRONIC KIDNEY DISEASE AT TABANAN GENERAL HOSPITAL ABSTRACT Background: Chronic kidney disease is a progressive decline in kidney function that can lead to anemia due to decreased erythropoietin production. Hemodialysis, as a renal replacement therapy, can affect hemoglobin levels through fluid removal processes that alter plasma volume. Objective: To determine the difference in hemoglobin levels before and after hemodialysis in patients with chronic kidney disease at RSUD Tabanan. Methods: This study used an analytical design with a pre-test and post-test approach. The sample consisted of 33 chronic kidney disease patients undergoing hemodialysis, selected using purposive sampling. Hemoglobin levels were measured before and after hemodialysis and analyzed using the Paired Sample T-Test. Results: The mean hemoglobin level before hemodialysis was 9.064 g/dL and increased to 9.421 g/dL after hemodialysis. Statistical analysis showed a significant difference (p = 0.016). However, this increase does not reflect a physiological improvement in anemia, as the levels remained below normal and were influenced by hemoconcentration due to reduced plasma volume. Conclusion: There is a significant difference in hemoglobin levels before and after hemodialysis; however, it does not indicate optimal improvement in anemia. Therefore, routine monitoring of hemoglobin levels remains necessary. Keywords: chronic kidney disease, hemodialysis, hemoglobin ANALISIS PERBEDAAN KADAR HEMOGLOBIN SEBELUM DAN SESUDAH HEMODIALISIS PADA PASIEN GAGAL GINJAL KRONIK DI RUMAH SAKIT UMUM TABANAN ABSTRAK Latar Belakang: Gagal ginjal kronik merupakan penurunan fungsi ginjal secara progresif yang dapat menyebabkan anemia akibat penurunan produksi eritropoietin. Hemodialisis sebagai terapi pengganti ginjal dapat memengaruhi kadar hemoglobin melalui proses pengeluaran cairan yang menyebabkan perubahan volume plasma. Tujuan: Mengetahui perbedaan kadar hemoglobin sebelum dan sesudah hemodialisis pada pasien gagal ginjal kronik di RSUD Tabanan. Metode: Penelitian ini merupakan penelitian analitik dengan pendekatan pre-test dan post-test. Sampel berjumlah 33 pasien gagal ginjal kronik yang menjalani hemodialisis. Teknik pengambilan sampel pada penelitian ini yaitu menggunakan teknik purposive sampling. Pemeriksaan kadar hemoglobin dilakukan sebelum dan sesudah hemodialisis, kemudian dianalisis menggunakan uji Paired Sample T-Test. Hasil: Rata-rata kadar hemoglobin sebelum hemodialisis sebesar 9,064 g/dL dan meningkat menjadi 9,421 g/dL setelah hemodialisis. Hasil uji statistik menunjukkan terdapat perbedaan yang signifikan (p = 0,016). Namun, peningkatan tersebut tidak mencerminkan perbaikan anemia secara fisiologis karena masih berada di bawah nilai normal dan dipengaruhi oleh hemokonsentrasi akibat penurunan volume plasma. Simpulan: Terdapat perbedaan yang signifikan antara kadar hemoglobin sebelum dan sesudah hemodialisis, namun belum menunjukkan perbaikan anemia secara optimal sehingga pemeriksaan kadar hemoglobin secara rutin tetap diperlukan. Kata kunci: gagal ginjal kronik, hemodialisis, hemoglobin
| Item Type: | Thesis (Diploma) |
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| Uncontrolled Keywords: | chronic kidney disease, hemodialysis, hemoglobin gagal ginjal kronik, hemodialisis, hemoglobin |
| Subjects: | Q Science > Q Science (General) R Medicine > RB Pathology |
| Divisions: | Jurusan Analis Kesehatan |
| Depositing User: | Paramita Ida Ayu Nia |
| Date Deposited: | 02 Sep 2026 00:44 |
| Last Modified: | 02 Sep 2026 00:44 |
| URI: | http://repository.poltekkes-denpasar.ac.id/id/eprint/20901 |
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