Dewi Sarihati, I Gusti Agung (2017) Makrofag Dan Aterosklerosis. Meditory: The Journal of Medical Laboratory, 5 (1). pp. 61-67. ISSN 2338-1159
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Abstract
Abstract Inflammation in atherogenesis occurs because of the interaction between leukocytes, platelets and cells of the blood vessel wall. Stimulation of atherosclerosis risk factors as well as hypercholesterolemia will increase the production of monocytes in the bone marrow. Monocytes enter the arteria and attach to the endothelial cells and turn into macrophages after arriving at the subendotel space. High LDL in hypercholerolemia will result in the occurrence of LDL oxidation to be phagocytosed by macrophages and thus transform into foam cells that are the early stages of atherogenesis. Increased activity of M1 macrophages will promote atherogenesis while increased M2 macrophage activity will result in improvement of lesions in the arteries. To reduce the occurrence of atherosclerosis is one of them by preventing the occurrence of inflammation in the walls of blood vesselst due to hypercholesterolaemia. Keywords: macrophages; atherosclerosis, inflammation
| Item Type: | Article |
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| Subjects: | Z Bibliography. Library Science. Information Resources > Z719 Libraries (General) |
| Divisions: | Jurusan Analis Kesehatan |
| Depositing User: | mrs Dewi Sarihati I G A |
| Date Deposited: | 02 Aug 2019 01:18 |
| Last Modified: | 02 Aug 2019 01:18 |
| URI: | http://repository.poltekkes-denpasar.ac.id/id/eprint/2256 |
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