HUBUNGAN KADAR ANTIBODI HEPATITIS B SURFACE DENGAN KADAR SERUM GLUTAMIC PYRUVIC TRANSAMINASE, SERUM GLUTAMIC OXALOACETIC TRANSAMINASE, DAN BILIRUBIN TOTAL

Dewi, Ni Putu Ditya Prabandari (2024) HUBUNGAN KADAR ANTIBODI HEPATITIS B SURFACE DENGAN KADAR SERUM GLUTAMIC PYRUVIC TRANSAMINASE, SERUM GLUTAMIC OXALOACETIC TRANSAMINASE, DAN BILIRUBIN TOTAL. Diploma thesis, Poltekkes Kemenkes Denpasar Jurusan Analis Kesehatan 2024.

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Abstract

HUBUNGAN KADAR ANTIBODI HEPATITIS B SURFACE DENGAN KADAR Serum Glutamic Pyruvic Transaminase, Serum Glutamic Oxaloacetic Transaminase, DAN BILIRUBIN TOTAL ABSTRAK Latar belakang Virus hepatitis B merupakan penyakit yang dapat menyebabkan fungsi lain dari organ hati terganggu. Tujuan penelitian ini adalah untuk mengetahui hubungan Kadar Antibodi Hepatitis B dengan Kadar SGOT, SGPT, dan Bilirubin. Metode menggunakan penelitian analitik kuantitatif dengan pendekatan cross sectional. Pengumpulan data dilakukan dengan pengambilan data primer yaitu sampel serum hepatitis B dan data sekunder yaitu kadar SGOT, kadar SGPT, kadar bilirubin, usia, jenis kelamin, dan riwayat penyakit. Hasil penelitian menunjukkan hubungan kadar antibodi hepatitis B dengan kadar SGOT ada hubungan signifikan dan tidak searah, karena nilai Sig. (2-tailed) sebesar 0,029 (<0,05) dan angka koefisien korelasi bernilai negatif yaitu -0,627. Hubungan kadar antibodi hepatitis B dengan kadar SGPT ada hubungan signifikan dan tidak searah, karena nilai Sig. (2-tailed) sebesar 0,003 (<0,05) dan angka koefisien korelasi bernilai negatif yaitu -0,616. Hubungan kadar antibodi hepatitis B dengan kadar bilirubin tidak ada hubungan signifikan dan menunjukkan hubungan yang searah, karena nilai Sig. (2-tailed) sebesar 0,809 (>0,05) dan angka koefisien korelasi bernilai positif yaitu 0,078. Kesimpulan pemeriksaan kadar antibodi hepatitis B dengan kadar SGOT dan SGPT menunjukkan korelasi negatif (tidak searah), sementara kadar antibodi hepatitis B dengan kadar bilirubin menunjukkan korelasi positif (searah) namun tidak signifikan. Kata Kunci: Hepatitis B, SGOT, SGPT, Bilirubin THE RELATIONSHIP OF HEPATITIS B SURFACE ANTIBODY LEVELS WITH THE LEVELS OF Serum Glutamic Pyruvic Transaminase, Serum Glutamic Oxaloacetic Transaminase, AND TOTAL BILIRUBIN ABSTRACT Background Hepatitis B virus is a disease that can cause other functions of the liver to be disrupted. Purpose of this study was to determine the relationship between Hepatitis B Antibody Levels and SGOT, SGPT and Bilirubin Levels. Method uses quantitative analytical research with a cross sectional approach. Data collection was carried out by collecting primary data, namely hepatitis B serum samples and secondary data, namely SGOT levels, SGPT levels, bilirubin levels, age, gender and disease history. Results of the study showed that there was a significant and unidirectional relationship between hepatitis B antibody levels and SGOT levels, because the Sig. (2-tailed) is 0.029 (<0.05) and the correlation coefficient is negative, namely -0.627. There is a significant and unidirectional relationship between hepatitis B antibody levels and SGPT levels, because the Sig. (2-tailed) is 0.003 (<0.05) and the correlation coefficient is negative, namely -0.616. There is no significant relationship between hepatitis B antibody levels and bilirubin levels and shows a unidirectional relationship, because the Sig. (2-tailed) is 0.809 (>0.05) and the correlation coefficient is positive, namely 0.078. Conclusion examination of hepatitis B antibody levels with SGOT and SGPT levels showed a negative correlation (not in the same direction), while hepatitis B antibody levels with bilirubin levels showed a positive (unidirectional) correlation but was not significant. Keywords: Hepatitis B, SGOT, SGPT, Bilirubin

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