(artikel) Antibacterial Activity of Legundi Leaf Extract (Vitex trifolia L.) with Betel Leaf Extract (Piper betle L.) against Staphylococcus aureus

Oka Suyasa, Ida Bagus (2022) (artikel) Antibacterial Activity of Legundi Leaf Extract (Vitex trifolia L.) with Betel Leaf Extract (Piper betle L.) against Staphylococcus aureus. SEAS (Sustainable Environment Agricultural Science), 6 (2). pp. 112-118. ISSN E-ISSN 2614-0934

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Abstract

One of the plants that have antibacterial compounds is legundi leaves and betel leaves. The combination of the two extracts is expected to provide a synergistic effect so that it can increase the inhibition of Staphylococcus aureus bacteria. This study used the disc diffusion test method to determine the antibacterial activity. The data obtained were analyzed using the Kolmogrov-Smirnov test and continued with the one-way Anova test. The average diameter of the inhibition zone in this study ranged from 6.43 mm to 18.63 mm where legundi extract had a medium category, betel extract had a moderate to strong category, and combined extracts had a strong category. The combination of ethanol extract of legundi leaves (Vitex trifolia Linn.) with betel leaves (Piper betle L. ) has antibacterial activity against Staphylococcus aureus growth in vitro, based on the results of the one way annova test with a significance value of p < 0.05. The combination of antibacterial compounds from legundi with betel nut with a ratio of 2:1 had a greater inhibitory power than the two single extracts. The smallest diameter of the inhibition zone in the two leaf extracts was at a concentration of 20% (betel leaf extract had an average of 8.17 while legundi leaf had an average of 7.78). Next is a concentration of 30% (betel leaf extract has an average of 9.53 while legundi leaf has an average of 7.27) and the highest is at a concentration of 40% (betel leaf extract has an average of 14.2 while legundi leaf has an average of 8.77).

Item Type: Article
Subjects: Q Science > Q Science (General)
Depositing User: Mr. Oka Suyasa Ida Bagus
Date Deposited: 13 Dec 2022 04:19
Last Modified: 13 Dec 2022 04:19
URI: http://repository.poltekkes-denpasar.ac.id/id/eprint/10189

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